Involvement of tumor suppressors PTEN and p53 in the formation of multiple subtypes of liposarcoma

Liposarcoma (LPS) is a type of soft tissue sarcoma that mostly occurs in adults, and in humans is characterized by amplifications of MDM2 and CDK4. The molecular pathogenesis of this malignancy is still poorly understood and, therefore, we developed a mouse model with conditional inactivation of PTE...

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Detalles Bibliográficos
Autores principales: Puzio-Kuter, A M, Laddha, S V, Castillo-Martin, M, Sun, Y, Cordon-Cardo, C, Chan, C S, Levine, A J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648325/
https://www.ncbi.nlm.nih.gov/pubmed/25822339
http://dx.doi.org/10.1038/cdd.2015.27

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