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Concordant analysis of KRAS, BRAF, PIK3CA mutations, and PTEN expression between primary colorectal cancer and matched metastases

Current data on the concordance of KRAS, BRAF, PIK3CA mutation status or PTEN expression status between primary tumors and metastases in colorectal cancer (CRC) are conflicting. We conducted a systematic review and meta-analysis to examine concordance and discordance of the status of these four biom...

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Detalles Bibliográficos
Autores principales: Mao, Chen, Wu, Xin-Yin, Yang, Zu-Yao, Threapleton, Diane Erin, Yuan, Jin-Qiu, Yu, Yuan-Yuan, Tang, Jin-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648436/
https://www.ncbi.nlm.nih.gov/pubmed/25639985
http://dx.doi.org/10.1038/srep08065

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