Hydroxyurea-Increased Fetal Hemoglobin Is Associated with Less Organ Damage and Longer Survival in Adults with Sickle Cell Anemia

BACKGROUND: Adults with sickle cell anemia (HbSS) are inconsistently treated with hydroxyurea. OBJECTIVES: We retrospectively evaluated the effects of elevating fetal hemoglobin with hydroxyurea on organ damage and survival in patients enrolled in our screening study between 2001 and 2010. METHODS:...

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Detalles Bibliográficos
Autores principales: Fitzhugh, Courtney D., Hsieh, Matthew M., Allen, Darlene, Coles, Wynona A., Seamon, Cassie, Ring, Michael, Zhao, Xiongce, Minniti, Caterina P., Rodgers, Griffin P., Schechter, Alan N., Tisdale, John F., Taylor, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648496/
https://www.ncbi.nlm.nih.gov/pubmed/26576059
http://dx.doi.org/10.1371/journal.pone.0141706

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