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Bispecific antibody releasing-mesenchymal stromal cell machinery for retargeting T cells towards acute myeloid leukemia blasts
Bispecific antibodies (bsAbs) engaging T cells are emerging as a promising immunotherapeutic tool for the treatment of hematologic malignancies. Because their low molecular mass, bsAbs have short half-lives. To achieve clinical responses, they have to be infused into patients continously, for a long...
Autores principales: | Aliperta, R, Cartellieri, M, Feldmann, A, Arndt, C, Koristka, S, Michalk, I, von Bonin, M, Ehninger, A, Bachmann, J, Ehninger, G, Bornhäuser, M, Bachmann, M P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648523/ https://www.ncbi.nlm.nih.gov/pubmed/26383821 http://dx.doi.org/10.1038/bcj.2015.73 |
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