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Ageing, autoimmunity and arthritis: Senescence of the B cell compartment – implications for humoral immunity
Immunosenescence is associated with a decline in both T and B lymphocyte function. Although aged individuals have normal numbers of B cells in the periphery and are capable of mounting robust humoral responses, the antibodies produced are generally of lower affinity and are less protective than thos...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC464870/ https://www.ncbi.nlm.nih.gov/pubmed/15225355 http://dx.doi.org/10.1186/ar1180 |