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Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis

Prostaglandin E synthase (PGES) including isoenzymes of membrane-associated PGES (mPGES)-1, mPGES-2, and cytosolic PGES (cPGES) is the recently identified terminal enzyme of the arachidonic acid cascade. PGES converts prostaglandin (PG)H(2 )to PGE(2 )downstream of cyclooxygenase (COX). We investigat...

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Detalles Bibliográficos
Autores principales:	Kojima, Fumiaki, Naraba, Hiroaki, Miyamoto, Satoshi, Beppu, Moroe, Aoki, Haruhito, Kawai, Shinichi
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2004
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC464891/ https://www.ncbi.nlm.nih.gov/pubmed/15225371 http://dx.doi.org/10.1186/ar1195

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