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Lipidomic and metabolomic characterization of a genetically modified mouse model of the early stages of human type 1 diabetes pathogenesis

The early mechanisms regulating progression towards beta cell failure in type 1 diabetes (T1D) are poorly understood, but it is generally acknowledged that genetic and environmental components are involved. The metabolomic phenotype is sensitive to minor variations in both, and accordingly reflects...

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Detalles Bibliográficos
Autores principales: Overgaard, Anne Julie, Weir, Jacquelyn M., De Souza, David Peter, Tull, Dedreia, Haase, Claus, Meikle, Peter J., Pociot, Flemming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648980/
https://www.ncbi.nlm.nih.gov/pubmed/26612984
http://dx.doi.org/10.1007/s11306-015-0889-1

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