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Mitochondrial Regulation of the Muscle Microenvironment in Critical Limb Ischemia
Critical limb ischemia (CLI) is the most severe clinical presentation of peripheral arterial disease and manifests as chronic limb pain at rest and/or tissue necrosis. Current clinical interventions are largely ineffective and therapeutic angiogenesis based trials have shown little efficacy, highlig...
Autores principales: | Ryan, Terence E., Schmidt, Cameron A., Green, Tom D., Brown, David A., Neufer, P. Darrell, McClung, Joseph M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649016/ https://www.ncbi.nlm.nih.gov/pubmed/26635622 http://dx.doi.org/10.3389/fphys.2015.00336 |
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