Cargando…
Vascular Platform to Define Hematopoietic Stem Cell Factors and Enhance Regenerative Hematopoiesis
Hematopoietic stem cells (HSCs) inhabit distinct microenvironments within the adult bone marrow (BM), which govern the delicate balance between HSC quiescence, self-renewal, and differentiation. Previous reports have proposed that HSCs localize to the vascular niche, comprised of endothelium and tig...
Autores principales: | Poulos, Michael G., Crowley, Michael J.P., Gutkin, Michael C., Ramalingam, Pradeep, Schachterle, William, Thomas, Jean-Leon, Elemento, Olivier, Butler, Jason M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649106/ https://www.ncbi.nlm.nih.gov/pubmed/26441307 http://dx.doi.org/10.1016/j.stemcr.2015.08.018 |
Ejemplares similares
-
DELETION OF THROMBOSPONDIN-1 PRESERVES HEMATOPOIETIC STEM CELL HEALTHSPAN DURING AGING
por: Ramalingam, Pradeep, et al.
Publicado: (2022) -
Endothelial mTOR maintains hematopoiesis during aging
por: Ramalingam, Pradeep, et al.
Publicado: (2020) -
Vascular Regulation of Hematopoietic Stem Cell Homeostasis, Regeneration, and Aging
por: Ramalingam, Pradeep, et al.
Publicado: (2021) -
Chronic activation of endothelial MAPK disrupts hematopoiesis via NFKB dependent inflammatory stress reversible by SCGF
por: Ramalingam, Pradeep, et al.
Publicado: (2020) -
An integrative view of the regulatory and transcriptional landscapes in mouse hematopoiesis
por: Xiang, Guanjue, et al.
Publicado: (2020)