Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition

Mostrar otras versiones (1)

Tools for rapid and efficient transgenesis in “safe harbor” loci in an isogenic context remain important to exploit the possibilities of human pluripotent stem cells (hPSCs). We created hPSC master cell lines suitable for FLPe recombinase-mediated cassette exchange (RMCE) in the AAVS1 locus that all...

Descripción completa

Detalles Bibliográficos
Autores principales: Ordovás, Laura, Boon, Ruben, Pistoni, Mariaelena, Chen, Yemiao, Wolfs, Esther, Guo, Wenting, Sambathkumar, Rangarajan, Bobis-Wozowicz, Sylwia, Helsen, Nicky, Vanhove, Jolien, Berckmans, Pieter, Cai, Qing, Vanuytsel, Kim, Eggermont, Kristel, Vanslembrouck, Veerle, Schmidt, Béla Z., Raitano, Susanna, Van Den Bosch, Ludo, Nahmias, Yaakov, Cathomen, Toni, Struys, Tom, Verfaillie, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649136/
https://www.ncbi.nlm.nih.gov/pubmed/26455413
http://dx.doi.org/10.1016/j.stemcr.2015.09.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649136/
https://www.ncbi.nlm.nih.gov/pubmed/26455413
http://dx.doi.org/10.1016/j.stemcr.2015.09.004

Ejemplares similares