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Eagle Effect in Nonreplicating Persister Mycobacteria

We determined the microbicidal activities of antibacterials against nonreplicating Mycobacterium smegmatis grown in a starvation-based Loebel model for persistence. Whereas most drugs lost their activity, fluoroquinolones retained lethal potency. Dose-response characterizations showed a paradoxical...

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Detalles Bibliográficos
Autores principales:	Wu, Mu-Lu, Tan, Jasmie, Dick, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2015
Materias:	Mechanisms of Action: Physiological Effects
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649170/ https://www.ncbi.nlm.nih.gov/pubmed/26349831 http://dx.doi.org/10.1128/AAC.01476-15

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