Neural Stem Cells Rescue Cognitive and Motor Dysfunction in a Transgenic Model of Dementia with Lewy Bodies through a BDNF-Dependent Mechanism

Accumulation of α-synuclein (α-syn) into insoluble aggregates occurs in several related disorders collectively referred to as synucleinopathies. To date, studies have used neural stem cells (NSCs) to examine questions about α-syn propagation, but have overlooked the therapeutic potential of NSC tran...

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Detalles Bibliográficos
Autores principales: Goldberg, Natalie R.S., Caesar, Jacqueline, Park, Ashley, Sedgh, Shawn, Finogenov, Gilana, Masliah, Eliezer, Davis, Joy, Blurton-Jones, Mathew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649255/
https://www.ncbi.nlm.nih.gov/pubmed/26489892
http://dx.doi.org/10.1016/j.stemcr.2015.09.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649255/
https://www.ncbi.nlm.nih.gov/pubmed/26489892
http://dx.doi.org/10.1016/j.stemcr.2015.09.008

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