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Progressive Chromatin Condensation and H3K9 Methylation Regulate the Differentiation of Embryonic and Hematopoietic Stem Cells
Epigenetic regulation serves as the basis for stem cell differentiation into distinct cell types, but it is unclear how global epigenetic changes are regulated during this process. Here, we tested the hypothesis that global chromatin organization affects the lineage potential of stem cells and that...
Autores principales: | Ugarte, Fernando, Sousae, Rebekah, Cinquin, Bertrand, Martin, Eric W., Krietsch, Jana, Sanchez, Gabriela, Inman, Margaux, Tsang, Herman, Warr, Matthew, Passegué, Emmanuelle, Larabell, Carolyn A., Forsberg, E. Camilla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649257/ https://www.ncbi.nlm.nih.gov/pubmed/26489895 http://dx.doi.org/10.1016/j.stemcr.2015.09.009 |
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