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Enhancer Analysis Unveils Genetic Interactions between TLX and SOX2 in Neural Stem Cells and In Vivo Reprogramming

The orphan nuclear receptor TLX is a master regulator of postnatal neural stem cell (NSC) self-renewal and neurogenesis; however, it remains unclear how TLX expression is precisely regulated in these tissue-specific stem cells. Here, we show that a highly conserved cis-element within the Tlx locus f...

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Detalles Bibliográficos
Autores principales:	Islam, Mohammed M., Smith, Derek K., Niu, Wenze, Fang, Sanhua, Iqbal, Nida, Sun, Guoqiang, Shi, Yanhong, Zhang, Chun-Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649261/ https://www.ncbi.nlm.nih.gov/pubmed/26607952 http://dx.doi.org/10.1016/j.stemcr.2015.09.015

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