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Induced Developmental Arrest of Early Hematopoietic Progenitors Leads to the Generation of Leukocyte Stem Cells

Self-renewal potential and multipotency are hallmarks of a stem cell. It is generally accepted that acquisition of such stemness requires rejuvenation of somatic cells through reprogramming of their genetic and epigenetic status. We show here that a simple block of cell differentiation is sufficient...

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Detalles Bibliográficos
Autores principales:	Ikawa, Tomokatsu, Masuda, Kyoko, Huijskens, Mirelle J.A.J., Satoh, Rumi, Kakugawa, Kiyokazu, Agata, Yasutoshi, Miyai, Tomohiro, Germeraad, Wilfred T.V., Katsura, Yoshimoto, Kawamoto, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649263/ https://www.ncbi.nlm.nih.gov/pubmed/26607950 http://dx.doi.org/10.1016/j.stemcr.2015.09.012

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