Case series of rhinocerebral mucormycosis occurring in diabetic patients

BACKGROUND: Rhinocerebral mucormycosis is a fatal infection typically affecting diabetic or immunosuppressed patients. In most cases, infection is caused by inhalation of fungal spores. Mortality rate of patients is very high (40-85%). CASE PRESENTATION: In this study, three diabetic patients with r...

Descripción completa

Detalles Bibliográficos
Autores principales: Mohammadi, Rasoul, Meidani, Mohsen, Mostafavizadeh, Kamyar, Iraj, Bijan, Hamedani, Pooria, Sayedain, Sayed Mohammad Amin, Mokhtari, Mojgan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Babol University of Medical Sciences 2015
Materias:
Case Series
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649276/
https://www.ncbi.nlm.nih.gov/pubmed/26644901
_version_ 1782401322558947328
author Mohammadi, Rasoul
Meidani, Mohsen
Mostafavizadeh, Kamyar
Iraj, Bijan
Hamedani, Pooria
Sayedain, Sayed Mohammad Amin
Mokhtari, Mojgan
author_facet Mohammadi, Rasoul
Meidani, Mohsen
Mostafavizadeh, Kamyar
Iraj, Bijan
Hamedani, Pooria
Sayedain, Sayed Mohammad Amin
Mokhtari, Mojgan
author_sort Mohammadi, Rasoul
collection PubMed
description BACKGROUND: Rhinocerebral mucormycosis is a fatal infection typically affecting diabetic or immunosuppressed patients. In most cases, infection is caused by inhalation of fungal spores. Mortality rate of patients is very high (40-85%). CASE PRESENTATION: In this study, three diabetic patients with rhinocerebral mucormycosis were presented. The etiologic agents of mucormycosis in two patients were isolated and identified by sequence analysis and data were registered in Gene bank database. CONCLUSION: In patients with mucoreosis, early detection, surgical excision and appropriate debridement, suitable antifungal therapy, and control of risk factors like diabetes mellitus are the main parameters of successful management of this lethal infection.
format Online
Article
Text
id pubmed-4649276
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Babol University of Medical Sciences
record_format MEDLINE/PubMed
spelling pubmed-46492762015-12-07 Case series of rhinocerebral mucormycosis occurring in diabetic patients Mohammadi, Rasoul Meidani, Mohsen Mostafavizadeh, Kamyar Iraj, Bijan Hamedani, Pooria Sayedain, Sayed Mohammad Amin Mokhtari, Mojgan Caspian J Intern Med Case Series BACKGROUND: Rhinocerebral mucormycosis is a fatal infection typically affecting diabetic or immunosuppressed patients. In most cases, infection is caused by inhalation of fungal spores. Mortality rate of patients is very high (40-85%). CASE PRESENTATION: In this study, three diabetic patients with rhinocerebral mucormycosis were presented. The etiologic agents of mucormycosis in two patients were isolated and identified by sequence analysis and data were registered in Gene bank database. CONCLUSION: In patients with mucoreosis, early detection, surgical excision and appropriate debridement, suitable antifungal therapy, and control of risk factors like diabetes mellitus are the main parameters of successful management of this lethal infection. Babol University of Medical Sciences 2015 /pmc/articles/PMC4649276/ /pubmed/26644901 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Series
Mohammadi, Rasoul
Meidani, Mohsen
Mostafavizadeh, Kamyar
Iraj, Bijan
Hamedani, Pooria
Sayedain, Sayed Mohammad Amin
Mokhtari, Mojgan
Case series of rhinocerebral mucormycosis occurring in diabetic patients
title Case series of rhinocerebral mucormycosis occurring in diabetic patients
title_full Case series of rhinocerebral mucormycosis occurring in diabetic patients
title_fullStr Case series of rhinocerebral mucormycosis occurring in diabetic patients
title_full_unstemmed Case series of rhinocerebral mucormycosis occurring in diabetic patients
title_short Case series of rhinocerebral mucormycosis occurring in diabetic patients
title_sort case series of rhinocerebral mucormycosis occurring in diabetic patients
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649276/
https://www.ncbi.nlm.nih.gov/pubmed/26644901
work_keys_str_mv AT mohammadirasoul caseseriesofrhinocerebralmucormycosisoccurringindiabeticpatients
AT meidanimohsen caseseriesofrhinocerebralmucormycosisoccurringindiabeticpatients
AT mostafavizadehkamyar caseseriesofrhinocerebralmucormycosisoccurringindiabeticpatients
AT irajbijan caseseriesofrhinocerebralmucormycosisoccurringindiabeticpatients
AT hamedanipooria caseseriesofrhinocerebralmucormycosisoccurringindiabeticpatients
AT sayedainsayedmohammadamin caseseriesofrhinocerebralmucormycosisoccurringindiabeticpatients
AT mokhtarimojgan caseseriesofrhinocerebralmucormycosisoccurringindiabeticpatients

Ejemplares similares