Cargando…

Galectin-3 inhibition using novel inhibitor GR-MD-02 improves survival and immune function while reducing tumor vasculature

Detalles Bibliográficos
Autores principales:	Linch, Stefanie, Kasiewicz, Melissa J, McNamara, Michael, Hilgart, Ian, Farhad, Mohammad, Redmond, William
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Poster Presentation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649323/ http://dx.doi.org/10.1186/2051-1426-3-S2-P306

Ejemplares similares

Combination OX40 agonism/CTLA-4 blockade with HER2 vaccination reverses T cell anergy and promotes survival in tumor-bearing mice
por: Linch, Stefanie, et al.
Publicado: (2015)

Combination OX40 agonism/CTLA-4 blockade with vaccination reverses anergy and primes tumor-specific CD8 T cells in mice with spontaneous prostate cancer
por: Linch, Stefanie N, et al.
Publicado: (2013)

Combined targeting of co-stimulatory (OX40) and co-inhibitory (CTLA-4) pathways elicits potent effector T cells capable of driving robust anti-tumor immunity
por: Redmond, William L, et al.
Publicado: (2013)

Biomarkers of survival statistics (boss) analytical platform
por: McNamara, Michael, et al.
Publicado: (2015)

Murine peripheral blood prognostic biomarkers for tumor survival following combination aCTLA-4 and aPD-1 treatment
por: Hilgart-Martiszus, Ian, et al.
Publicado: (2015)

Common gamma chain (γc) cytokines differentially potentiate TNFR family signaling in antigen-activated CD8(+) T cells
por: McNamara, Michael J, et al.
Publicado: (2014)

Galectin-3 inhibition with belapectin combined with anti-OX40 therapy reprograms the tumor microenvironment to favor anti-tumor immunity
por: Sturgill, Elizabeth R., et al.
Publicado: (2021)

OX40 Agonists and Combination Immunotherapy: Putting the Pedal to the Metal
por: Linch, Stefanie N., et al.
Publicado: (2015)

NKTR-214 immunotherapy synergizes with radiotherapy to stimulate systemic CD8(+) T cell responses capable of curing multi-focal cancer
por: Walker, Joshua M, et al.
Publicado: (2020)

Ipilimumab treatment decreases circulating Tregs and GrMDSC while enhancing CD4+ T cell activation
por: Pico de Coaña, Yago, et al.
Publicado: (2015)

Discovery of Novel GR Ligands toward Druggable GR Antagonist Conformations Identified by MD Simulations and Markov State Model Analysis
por: Hu, Xueping, et al.
Publicado: (2021)

Maldevelopment of the Immature Pulmonary Vasculature and Prolonged Patency of the Ductus Arteriosus: Association or Cause?
por: McNamara, Patrick J., et al.
Publicado: (2022)

Enhancement of anti-tumor efficacy of immune checkpoint blockade by alpha-TEA
por: Redmond, William L., et al.
Publicado: (2023)

The role of Galectin-3 in modulating tumor growth and immunosuppression within the tumor microenvironment
por: Farhad, Mohammad, et al.
Publicado: (2018)

Galectin-3 and galectin-3 binding protein in rheumatoid arthritis
por: Ohshima, S, et al.
Publicado: (2003)

GR Dimerization and the Impact of GR Dimerization on GR Protein Stability and Half-Life
por: Louw, Ann
Publicado: (2019)

Combinatorial immunotherapeutic approaches to restore the function of anergic tumor-reactive cytotoxic CD8(+) T cells
por: Redmond, William L., et al.
Publicado: (2016)

Combined OX40 ligation plus CTLA-4 blockade: More than the sum of its parts
por: Linch, Stefanie N, et al.
Publicado: (2014)

How do I steer this thing? Using dendritic cell targeted vaccination to more effectively guide the antitumor immune response with combination immunotherapy
por: Linch, Stefanie N., et al.
Publicado: (2016)

Preparative immunotherapy with anti-OX40 and anti-CTLA4 improves the response to chemotherapy
por: Friedman, David J, et al.
Publicado: (2014)

Utility and variability of three non-invasive liver fibrosis imaging modalities to evaluate efficacy of GR-MD-02 in subjects with NASH and bridging fibrosis during a phase-2 randomized clinical trial
por: Harrison, Stephen A., et al.
Publicado: (2018)

Efficacy and utility of preemptive anti-Gr(+) coverage in selected critically ill patients
por: Todorova, VT, et al.
Publicado: (2013)

Targeting the tumor vasculature with TEM8-specific T cells
por: Williams, LaTerrica C, et al.
Publicado: (2014)

Integrating skin and vasculature in a Multi-Organ-Chip Platform
por: Schimek, Katharina, et al.
Publicado: (2015)

Neoadjuvant treatment: the MD Anderson experience
por: Hortobagyi, GN
Publicado: (2005)

MP29-02* reduces eosinophil survival induced by epithelial cell secretions from nasal mucosa
por: Roca-Ferrer, Jordi, et al.
Publicado: (2015)

Structural and functional evaluation of the peripheral vasculature in patients with PAD using MRI
por: Englund, Erin K, et al.
Publicado: (2015)

OA02.02. Effect of MBSR and psychological state on inflammatory markers in HIV positive adults
por: Weston, E, et al.
Publicado: (2012)

Impaired Spermatogenesis and gr/gr Deletions Related to Y Chromosome Haplogroups in Korean Men
por: Choi, Jin, et al.
Publicado: (2012)

Process evaluation in drugs trials within adult learning disability populations: a systematic review
por: Randell, Elizabeth, et al.
Publicado: (2015)

In vivo function of galectin-3 in motile cilia of airway epithelium
por: Delacour, D, et al.
Publicado: (2012)

0737. Statins protect the vasculature from excessive angpt-2 production in sepsis
por: Thamm, K, et al.
Publicado: (2014)

PA02.02. A comprehensive review of “Vaidya Vinoda” manuscript with reference to formulations and pharmaceutical procedures
por: Vyas, Ramakant
Publicado: (2013)

P34.02 The Inhibitory Effect of Cisplatin, Paclitaxel, and Pemetrexed on the Growth of PC9GR Cells During the COVID-19 Pandemic
por: Mohiuddin, M., et al.
Publicado: (2021)

Description of the GR configuration for LEP
por: Keil, Eberhard, et al.
Publicado: (1993)

Recommendation from GrACQ
por: Faisandel, L
Publicado: (2012)

P02.37. Mindfulness for caregivers
por: Bloom, P, et al.
Publicado: (2012)

P02.184. Abstract withdrawn
Publicado: (2012)

Enhancing clinical and immunological effects of anti-PD-1 with belapectin, a galectin-3 inhibitor
por: Curti, Brendan D, et al.
Publicado: (2021)

Myocardial vasculature: the third significant contributor to MR diffusion signals in the isolated rabbit heart
por: Hwang, Min-Sig, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_dogrgksd4ibivva69emrlfu042