Cargando…

Mechanisms of three-dimensional growth of thyroid cells during long-term simulated microgravity

Three-dimensional multicellular spheroids (MCS) of human cells are important in cancer research. We investigated possible mechanisms of MCS formation of thyroid cells. Both, normal Nthy-ori 3–1 thyroid cells and the poorly differentiated follicular thyroid cancer cells FTC-133 formed MCS within 7 an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kopp, Sascha, Warnke, Elisabeth, Wehland, Markus, Aleshcheva, Ganna, Magnusson, Nils E., Hemmersbach, Ruth, Juhl Corydon, Thomas, Bauer, Johann, Infanger, Manfred, Grimm, Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649336/ https://www.ncbi.nlm.nih.gov/pubmed/26576504 http://dx.doi.org/10.1038/srep16691

Ejemplares similares

Fighting Thyroid Cancer with Microgravity Research
por: Krüger, Marcus, et al.
Publicado: (2019)

Pathways Regulating Spheroid Formation of Human Follicular Thyroid Cancer Cells under Simulated Microgravity Conditions: A Genetic Approach
por: Riwaldt, Stefan, et al.
Publicado: (2016)

Common Effects on Cancer Cells Exerted by a Random Positioning Machine and a 2D Clinostat
por: Svejgaard, Benjamin, et al.
Publicado: (2015)

Spheroid formation of human thyroid cancer cells under simulated microgravity: a possible role of CTGF and CAV1
por: Warnke, Elisabeth, et al.
Publicado: (2014)

Interleukin-6 Expression under Gravitational Stress Due to Vibration and Hypergravity in Follicular Thyroid Cancer Cells
por: Ma, Xiao, et al.
Publicado: (2013)

Identifications of novel mechanisms in breast cancer cells involving duct-like multicellular spheroid formation after exposure to the Random Positioning Machine
por: Kopp, Sascha, et al.
Publicado: (2016)

Dexamethasone Inhibits Spheroid Formation of Thyroid Cancer Cells Exposed to Simulated Microgravity
por: Melnik, Daniela, et al.
Publicado: (2020)

Simulated Microgravity Influences VEGF, MAPK, and PAM Signaling in Prostate Cancer Cells
por: Hybel, Trine Engelbrecht, et al.
Publicado: (2020)

Short-Term Microgravity Influences Cell Adhesion in Human Breast Cancer Cells
por: Nassef, Mohamed Zakaria, et al.
Publicado: (2019)

Tissue Engineering of Cartilage Using a Random Positioning Machine
por: Wehland, Markus, et al.
Publicado: (2020)

The Impact of Simulated and Real Microgravity on Bone Cells and Mesenchymal Stem Cells
por: Ulbrich, Claudia, et al.
Publicado: (2014)

Semantic Analysis of Posttranslational Modification of Proteins Accumulated in Thyroid Cancer Cells Exposed to Simulated Microgravity
por: Bauer, Johann, et al.
Publicado: (2018)

Differential gene expression of human chondrocytes cultured under short-term altered gravity conditions during parabolic flight maneuvers
por: Wehland, Markus, et al.
Publicado: (2015)

Changes in Exosome Release in Thyroid Cancer Cells after Prolonged Exposure to Real Microgravity in Space
por: Wise, Petra M., et al.
Publicado: (2021)

Prolonged Exposure to Simulated Microgravity Changes Release of Small Extracellular Vesicle in Breast Cancer Cells
por: Wise, Petra M., et al.
Publicado: (2022)

Three-Dimensional Growth of Prostate Cancer Cells Exposed to Simulated Microgravity
por: Dietrichs, Dorothea, et al.
Publicado: (2022)

Microgravity Affects Thyroid Cancer Cells during the TEXUS-53 Mission Stronger than Hypergravity
por: Kopp, Sascha, et al.
Publicado: (2018)

The Importance of Caveolin-1 as Key-Regulator of Three-Dimensional Growth in Thyroid Cancer Cells Cultured under Real and Simulated Microgravity Conditions
por: Riwaldt, Stefan, et al.
Publicado: (2015)

Role of Apoptosis in Wound Healing and Apoptosis Alterations in Microgravity
por: Riwaldt, Stefan, et al.
Publicado: (2021)

Morphological and Molecular Changes in Juvenile Normal Human Fibroblasts Exposed to Simulated Microgravity
por: Buken, Christoph, et al.
Publicado: (2019)

Science between Bioreactors and Space Research—Response to Comments by Joseph J. Bevelacqua et al. on “Dexamethasone Inhibits Spheroid Formation of Thyroid Cancer Cells Exposed to Simulated Microgravity”
por: Krüger, Marcus, et al.
Publicado: (2020)

The Fight against Cancer by Microgravity: The Multicellular Spheroid as a Metastasis Model
por: Grimm, Daniela, et al.
Publicado: (2022)

Insight in Adhesion Protein Sialylation and Microgravity Dependent Cell Adhesion—An Omics Network Approach
por: Bauer, Thomas J., et al.
Publicado: (2020)

Real Microgravity Influences the Cytoskeleton and Focal Adhesions in Human Breast Cancer Cells
por: Nassef, Mohamed Zakaria, et al.
Publicado: (2019)

Changes in Morphology, Gene Expression and Protein Content in Chondrocytes Cultured on a Random Positioning Machine
por: Aleshcheva, Ganna, et al.
Publicado: (2013)

Changes in Exosomal miRNA Composition in Thyroid Cancer Cells after Prolonged Exposure to Real Microgravity in Space
por: Wise, Petra M., et al.
Publicado: (2021)

The effects of microgravity on differentiation and cell growth in stem cells and cancer stem cells
por: Grimm, Daniela, et al.
Publicado: (2020)

The CellBox-2 Mission to the International Space Station: Thyroid Cancer Cells in Space
por: Melnik, Daniela, et al.
Publicado: (2021)

Biomarkers for Anti-Angiogenic Therapy in Cancer
por: Wehland, Markus, et al.
Publicado: (2013)

Breast Cancer Cells in Microgravity: New Aspects for Cancer Research
por: Nassef, Mohamed Zakaria, et al.
Publicado: (2020)

Pazopanib, Cabozantinib, and Vandetanib in the Treatment of Progressive Medullary Thyroid Cancer with a Special Focus on the Adverse Effects on Hypertension
por: Milling, Rikke Vilsbøll, et al.
Publicado: (2018)

Proteome Analysis of Human Follicular Thyroid Cancer Cells Exposed to the Random Positioning Machine
por: Bauer, Johann, et al.
Publicado: (2017)

Influence of Microgravity on Apoptosis in Cells, Tissues, and Other Systems In Vivo and In Vitro
por: Prasad, Binod, et al.
Publicado: (2020)

The Adverse Effect of Hypertension in the Treatment of Thyroid Cancer with Multi-Kinase Inhibitors
por: Ancker, Ole Vincent, et al.
Publicado: (2017)

Microgravity-Related Changes in Bone Density and Treatment Options: A Systematic Review
por: Baran, Ronni, et al.
Publicado: (2022)

Current Knowledge about the Impact of Microgravity on Gene Regulation
por: Corydon, Thomas J., et al.
Publicado: (2023)

Translation from Microgravity Research to Earth Application
por: Grimm, Daniela, et al.
Publicado: (2022)

In Prostate Cancer Cells Cytokines Are Early Responders to Gravitational Changes Occurring in Parabolic Flights
por: Schulz, Herbert, et al.
Publicado: (2022)

Alteration of Cytoskeleton Morphology and Gene Expression in Human Breast Cancer Cells under Simulated Microgravity
por: Strube, Florian, et al.
Publicado: (2020)

Alterations of Growth and Focal Adhesion Molecules in Human Breast Cancer Cells Exposed to the Random Positioning Machine
por: Sahana, Jayashree, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_gc5kld9820vf4nrcot72filmt3