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Atypical PKC-iota Controls Stem Cell Expansion via Regulation of the Notch Pathway

The number of stem/progenitor cells available can profoundly impact tissue homeostasis and the response to injury or disease. Here, we propose that an atypical PKC, Prkci, is a key player in regulating the switch from an expansion to a differentiation/maintenance phase via regulation of Notch, thus...

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Detalles Bibliográficos
Autores principales:	Mah, In Kyoung, Soloff, Rachel, Hedrick, Stephen M., Mariani, Francesca V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649379/ https://www.ncbi.nlm.nih.gov/pubmed/26527382 http://dx.doi.org/10.1016/j.stemcr.2015.09.021

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