Cargando…

Identification and isolation of high avidity tumor-specific CD8 T cells by experimentally assessing pMHC-TCR binding parameters with soluble pMHC complexes

Detalles Bibliográficos
Autores principales:	Schmidt, Julien, Hebeisen, Michael, Guillaume, Philippe, Magnin, Morgane, Rufer, Nathalie, Luescher, Immanuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Poster Presentation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649411/ http://dx.doi.org/10.1186/2051-1426-3-S2-P263

Ejemplares similares

TCR/pMHC Optimized Protein crystallization Screen
por: Bulek, Anna M., et al.
Publicado: (2012)

Force Measurements of TCR/pMHC Recognition at T Cell Surface
por: Puech, Pierre-Henri, et al.
Publicado: (2011)

The coordination of unprotonated peptide tertiary structure as a metric of pMHC–TCR functional avidity
por: Antipas, Georgios S.E., et al.
Publicado: (2015)

TCR–pMHC bond conformation controls TCR ligand discrimination
por: Sasmal, Dibyendu K., et al.
Publicado: (2019)

Genome-wide structural modelling of TCR-pMHC interactions
por: Liu, I-Hsin, et al.
Publicado: (2013)

TCR/pMHC Interaction: Phenotypic Model for an Unsolved Enigma
por: Gálvez, Jesús, et al.
Publicado: (2016)

Integrating Experiment and Theory to Understand TCR-pMHC Dynamics
por: Buckle, Ashley M., et al.
Publicado: (2018)

Rapid screening of TCR-pMHC interactions by the YAMTAD system
por: Wang, Lihui, et al.
Publicado: (2022)

Information-Driven Docking for TCR-pMHC Complex Prediction
por: Peacock, Thomas, et al.
Publicado: (2021)

The Enigmatic Nature of the TCR-pMHC Interaction: Implications for CAR-T and TCR-T Engineering
por: Shevyrev, D. V., et al.
Publicado: (2022)

The kinetics of two dimensional TCR and pMHC interactions determine T cell responsiveness
por: Huang, Jun, et al.
Publicado: (2010)

Structural Features of the αβTCR Mechanotransduction Apparatus That Promote pMHC Discrimination
por: Brazin, Kristine N., et al.
Publicado: (2015)

A unifying mathematical framework for experimental TCR-pMHC kinetic constants
por: Faro, Jose, et al.
Publicado: (2017)

TCRpMHCmodels: Structural modelling of TCR-pMHC class I complexes
por: Jensen, Kamilla Kjærgaard, et al.
Publicado: (2019)

Immunological Mechanisms of Metal Allergies and the Nickel-Specific TCR-pMHC Interface
por: Riedel, Franziska, et al.
Publicado: (2021)

Potent T cell agonism mediated by a very rapid TCR/pMHC interaction
por: Boulter, Jonathan M, et al.
Publicado: (2007)

Molecular Dynamics Simulations Reveal Canonical Conformations in Different pMHC/TCR Interactions
por: Alba, Josephine, et al.
Publicado: (2020)

Understanding TR Binding to pMHC Complexes: How Does a TR Scan Many pMHC Complexes yet Preferentially Bind to One
por: Khan, Javed Mohammed, et al.
Publicado: (2011)

Epitope Flexibility and Dynamic Footprint Revealed by Molecular Dynamics of a pMHC-TCR Complex
por: Reboul, Cyril F., et al.
Publicado: (2012)

Direct single molecule measurement of TCR triggering by agonist pMHC in living primary T cells
por: O'Donoghue, Geoff P, et al.
Publicado: (2013)

Measuring TCR-pMHC Binding In Situ using a FRET-based Microscopy Assay
por: Axmann, Markus, et al.
Publicado: (2015)

Performance comparison of TCR-pMHC prediction tools reveals a strong data dependency
por: Deng, Lihua, et al.
Publicado: (2023)

The quantum chemical causality of pMHC-TCR biological avidity: Peptide atomic coordination data and the electronic state of agonist N termini
por: Antipas, Georgios S.E., et al.
Publicado: (2015)

MIX-TPI: a flexible prediction framework for TCR–pMHC interactions based on multimodal representations
por: Yang, Minghao, et al.
Publicado: (2023)

Fluctuations in T cell receptor and pMHC interactions regulate T cell activation
por: Egan, Joseph R., et al.
Publicado: (2022)

Conformation-selective rather than avidity-based binding to tumor associated antigen derived peptide-MHC enables targeting of WT1-pMHC low expressing cancer cells by anti-WT1-pMHC/CD3 T cell engagers
por: Walseng, Even, et al.
Publicado: (2023)

Quantum dot/pMHC multimers vs. phycoerythrin/pMHC tetramers for identification of HLA-A*0201-restricted pHBV core antigen(18–27)-specific T cells
por: Zhu, Jianmeng, et al.
Publicado: (2017)

TCR Triggering by pMHC Ligands Tethered on Surfaces via Poly(Ethylene Glycol) Depends on Polymer Length
por: Ma, Zhengyu, et al.
Publicado: (2014)

Intramolecular Domain Movements of Free and Bound pMHC and TCR Proteins: A Molecular Dynamics Simulation Study
por: Karch, Rudolf, et al.
Publicado: (2019)

Intrinsic CD4(+) T cell sensitivity and response to pathogen are set and sustained by avidity for thymic and peripheral self-pMHC
por: Persaud, Stephen P., et al.
Publicado: (2014)

n-3 Polyunsaturated Fatty Acids Impede the TCR Mobility and the TCR–pMHC Interaction of Anti-Viral CD8(+) T Cells
por: Lim, Younghyun, et al.
Publicado: (2020)

PAComplex: a web server to infer peptide antigen families and binding models from TCR–pMHC complexes
por: Liu, I-Hsin, et al.
Publicado: (2011)

The Full Model of the pMHC-TCR-CD3 Complex: A Structural and Dynamical Characterization of Bound and Unbound States
por: Alba, Josephine, et al.
Publicado: (2022)

DockTope: a Web-based tool for automated pMHC-I modelling
por: Menegatti Rigo, Maurício, et al.
Publicado: (2015)

A Strategy for Selective Deletion of Autoimmunity-Related T Cells by pMHC-Targeted Delivery
por: Goldberg, Shalom D., et al.
Publicado: (2021)

Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC
por: Sušac, Lukas, et al.
Publicado: (2022)

Is TCR/pMHC Affinity a Good Estimate of the T-cell Response? An Answer Based on Predictions From 12 Phenotypic Models
por: Gálvez, Jesús, et al.
Publicado: (2019)

A general chemical crosslinking strategy for structural analyses of weakly interacting proteins applied to preTCR–pMHC complexes
por: Mizsei, Réka, et al.
Publicado: (2021)

Conformational flexibility of a free and TCR-bound pMHC-I protein investigated by long-term molecular dynamics simulations
por: Tomasiak, Lisa, et al.
Publicado: (2022)

The complex and specific pMHC interactions with diverse HIV-1 TCR clonotypes reveal a structural basis for alterations in CTL function
por: Xia, Zhen, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_6utisgaj49akvloevrs0k6uq2s