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Sodium channel-inhibiting drugs and survival of breast, colon and prostate cancer: a population-based study

Metastasis is the leading cause of cancer-related deaths. Voltage-gated sodium channels (VGSCs) regulate invasion and metastasis. Several VGSC-inhibiting drugs reduce metastasis in murine cancer models. We aimed to test the hypothesis that patients taking VGSC-inhibiting drugs who developed cancer l...

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Detalles Bibliográficos
Autores principales: Fairhurst, Caroline, Watt, Ian, Martin, Fabiola, Bland, Martin, Brackenbury, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649474/
https://www.ncbi.nlm.nih.gov/pubmed/26577038
http://dx.doi.org/10.1038/srep16758