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Synergistic anti-tumor activity and inhibition of angiogenesis by cotargeting of oncogenic and death receptor pathways in human melanoma

Improving treatment of advanced melanoma may require the development of effective strategies to overcome resistance to different anti-tumor agents and to counteract relevant pro-tumoral mechanisms in the microenvironment. Here we provide preclinical evidence that these goals can be achieved in most...

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Detalles Bibliográficos
Autores principales: Grazia, G, Vegetti, C, Benigni, F, Penna, I, Perotti, V, Tassi, E, Bersani, I, Nicolini, G, Canevari, S, Carlo-Stella, C, Gianni, A M, Mortarini, R, Anichini, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649516/
https://www.ncbi.nlm.nih.gov/pubmed/25275595
http://dx.doi.org/10.1038/cddis.2014.410