Inhibition of human positive cofactor 4 radiosensitizes human esophageal squmaous cell carcinoma cells by suppressing XLF-mediated nonhomologous end joining

Radiotherapy has the widest application to esophageal squamous cell carcinoma (ESCC) patients. Factors associated with DNA damage repair have been shown to function in cell radiosensitivity. Human positive cofactor 4 (PC4) has a role in nonhomologous end joining (NHEJ) and is involved in DNA damage...

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Detalles Bibliográficos
Autores principales: Qian, D, Zhang, B, Zeng, X-L, Le Blanc, J M, Guo, Y-H, Xue, C, Jiang, C, Wang, H-H, Zhao, T-S, Meng, M-B, Zhao, L-J, Hao, J-H, Wang, P, Xie, D, Lu, B, Yuan, Z-Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649520/
https://www.ncbi.nlm.nih.gov/pubmed/25321468
http://dx.doi.org/10.1038/cddis.2014.416

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