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MUC1 extracellular domain confers resistance of epithelial cancer cells to anoikis

Anoikis, a special apoptotic process occurring in response to loss of cell adhesion to the extracellular matrix, is a fundamental surveillance process for maintaining tissue homeostasis. Resistance to anoikis characterises cancer cells and is a pre-requisite for metastasis. This study shows that ove...

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Detalles Bibliográficos
Autores principales: Zhao, Q, Piyush, T, Chen, C, Hollingsworth, M A, Hilkens, J, Rhodes, J M, Yu, L-G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649521/
https://www.ncbi.nlm.nih.gov/pubmed/25275599
http://dx.doi.org/10.1038/cddis.2014.421