A Smoothened receptor agonist is neuroprotective and promotes regeneration after ischemic brain injury

Ischemic stroke occurs as a result of blood supply interruption to the brain causing tissue degeneration, patient disabilities or death. Currently, treatment of ischemic stroke is limited to thrombolytic therapy with a narrow time window of administration. The sonic hedgehog (Shh) signaling pathway...

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Detalles Bibliográficos
Autores principales: Chechneva, O V, Mayrhofer, F, Daugherty, D J, Krishnamurty, R G, Bannerman, P, Pleasure, D E, Deng, W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649529/
https://www.ncbi.nlm.nih.gov/pubmed/25341035
http://dx.doi.org/10.1038/cddis.2014.446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649529/
https://www.ncbi.nlm.nih.gov/pubmed/25341035
http://dx.doi.org/10.1038/cddis.2014.446

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