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Co-expression of POU4F2/Brn-3b with p53 may be important for controlling expression of pro-apoptotic genes in cardiomyocytes following ischaemic/hypoxic insults

Cardiomyocyte death following ischaemic/hypoxic injury causes irreversible damage to cardiac function and contributes to chronic diseases such as heart failure. Understanding the mechanisms associated with myocyte loss under these conditions can help to identify strategies to minimise/abrogate such...

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Detalles Bibliográficos
Autores principales: Budhram-Mahadeo, V, Fujita, R, Bitsi, S, Sicard, P, Heads, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649532/
https://www.ncbi.nlm.nih.gov/pubmed/25356872
http://dx.doi.org/10.1038/cddis.2014.452