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Application of artificial neural network to investigate the effects of 5-fluorouracil on ribonucleotides and deoxyribonucleotides in HepG2 cells

Endogenous ribonucleotides and deoxyribonucleotides are essential metabolites that play important roles in a broad range of key cellular functions. Their intracellular levels could also reflect the action of nucleoside analogues. We investigated the effects of 5-fluorouracil (5-FU) on ribonucleotide...

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Detalles Bibliográficos
Autores principales: Guo, Jianru, Chen, QianQian, Lam, Christopher Wai Kei, Wang, Caiyun, Wong, Vincent Kam Wai, Xu, Fengguo, Jiang, ZhiHong, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649619/
https://www.ncbi.nlm.nih.gov/pubmed/26578061
http://dx.doi.org/10.1038/srep16861