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Application of artificial neural network to investigate the effects of 5-fluorouracil on ribonucleotides and deoxyribonucleotides in HepG2 cells
Endogenous ribonucleotides and deoxyribonucleotides are essential metabolites that play important roles in a broad range of key cellular functions. Their intracellular levels could also reflect the action of nucleoside analogues. We investigated the effects of 5-fluorouracil (5-FU) on ribonucleotide...
Autores principales: | Guo, Jianru, Chen, QianQian, Lam, Christopher Wai Kei, Wang, Caiyun, Wong, Vincent Kam Wai, Xu, Fengguo, Jiang, ZhiHong, Zhang, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649619/ https://www.ncbi.nlm.nih.gov/pubmed/26578061 http://dx.doi.org/10.1038/srep16861 |
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