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MicroRNAs and Their Targets Are Differentially Regulated in Adult and Neonatal Mouse CD8+ T Cells
Immunological memory, which protects organisms from re-infection, is a hallmark of the mammalian adaptive immune system and the underlying principle of vaccination. In early life, however, mice and other mammals are deficient at generating memory CD8+ T cells, which protect organisms from intracellu...
Autores principales: | Wissink, Erin M., Smith, Norah L., Spektor, Roman, Rudd, Brian D., Grimson, Andrew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649632/ https://www.ncbi.nlm.nih.gov/pubmed/26416483 http://dx.doi.org/10.1534/genetics.115.179176 |
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