Complementation of Yeast Genes with Human Genes as an Experimental Platform for Functional Testing of Human Genetic Variants

While the pace of discovery of human genetic variants in tumors, patients, and diverse populations has rapidly accelerated, deciphering their functional consequence has become rate-limiting. Using cross-species complementation, model organisms like the budding yeast, Saccharomyces cerevisiae, can be...

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Detalles Bibliográficos
Autores principales: Hamza, Akil, Tammpere, Erik, Kofoed, Megan, Keong, Christelle, Chiang, Jennifer, Giaever, Guri, Nislow, Corey, Hieter, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2015
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649650/
https://www.ncbi.nlm.nih.gov/pubmed/26354769
http://dx.doi.org/10.1534/genetics.115.181099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649650/
https://www.ncbi.nlm.nih.gov/pubmed/26354769
http://dx.doi.org/10.1534/genetics.115.181099

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