Differential immunogenicity between HAdV-5 and chimpanzee adenovirus vector ChAdOx1 is independent of fiber and penton RGD loop sequences in mice

Replication defective adenoviruses are promising vectors for the delivery of vaccine antigens. However, the potential of a vector to elicit transgene-specific adaptive immune responses is largely dependent on the viral serotype used. HAdV-5 (Human adenovirus C) vectors are more immunogenic than chim...

Descripción completa

Detalles Bibliográficos
Autores principales: Dicks, Matthew D. J., Spencer, Alexandra J., Coughlan, Lynda, Bauza, Karolis, Gilbert, Sarah C., Hill, Adrian V. S., Cottingham, Matthew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649739/
https://www.ncbi.nlm.nih.gov/pubmed/26576856
http://dx.doi.org/10.1038/srep16756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649739/
https://www.ncbi.nlm.nih.gov/pubmed/26576856
http://dx.doi.org/10.1038/srep16756

Ejemplares similares