Clozapine-induced Supraventricular Tachycardia and its Treatment with Verapamil

Clozapine is known to be an effective antipsychotic for schizophrenia. Cardiovascular complications associated with initiation of clozapine include tachycardia, postural hypotension, and myocarditis. Factors associated with development of cardiovascular adverse events are not clearly known, and dose...

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Autores principales: Settem, Jagadeesh V. V., Trivedi, Satyakant, Kamath, Avinash G., Behere, Rishikesh V., Kanaradi, Haridas, Bhat, Sripathy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649798/
https://www.ncbi.nlm.nih.gov/pubmed/26664091
http://dx.doi.org/10.4103/0253-7176.162925
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author Settem, Jagadeesh V. V.
Trivedi, Satyakant
Kamath, Avinash G.
Behere, Rishikesh V.
Kanaradi, Haridas
Bhat, Sripathy M.
author_facet Settem, Jagadeesh V. V.
Trivedi, Satyakant
Kamath, Avinash G.
Behere, Rishikesh V.
Kanaradi, Haridas
Bhat, Sripathy M.
author_sort Settem, Jagadeesh V. V.
collection PubMed
description Clozapine is known to be an effective antipsychotic for schizophrenia. Cardiovascular complications associated with initiation of clozapine include tachycardia, postural hypotension, and myocarditis. Factors associated with development of cardiovascular adverse events are not clearly known, and dose titration has been described to be one among the associated risk factors. We report a case of a 45-year-old man with treatment resistant schizophrenia who developed supraventricular tachycardia during initiation of clozapine and discuss the role of verapamil in its successful management.
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spelling pubmed-46497982015-12-10 Clozapine-induced Supraventricular Tachycardia and its Treatment with Verapamil Settem, Jagadeesh V. V. Trivedi, Satyakant Kamath, Avinash G. Behere, Rishikesh V. Kanaradi, Haridas Bhat, Sripathy M. Indian J Psychol Med Case Report Clozapine is known to be an effective antipsychotic for schizophrenia. Cardiovascular complications associated with initiation of clozapine include tachycardia, postural hypotension, and myocarditis. Factors associated with development of cardiovascular adverse events are not clearly known, and dose titration has been described to be one among the associated risk factors. We report a case of a 45-year-old man with treatment resistant schizophrenia who developed supraventricular tachycardia during initiation of clozapine and discuss the role of verapamil in its successful management. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4649798/ /pubmed/26664091 http://dx.doi.org/10.4103/0253-7176.162925 Text en Copyright: © Indian Journal of Psychological Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Settem, Jagadeesh V. V.
Trivedi, Satyakant
Kamath, Avinash G.
Behere, Rishikesh V.
Kanaradi, Haridas
Bhat, Sripathy M.
Clozapine-induced Supraventricular Tachycardia and its Treatment with Verapamil
title Clozapine-induced Supraventricular Tachycardia and its Treatment with Verapamil
title_full Clozapine-induced Supraventricular Tachycardia and its Treatment with Verapamil
title_fullStr Clozapine-induced Supraventricular Tachycardia and its Treatment with Verapamil
title_full_unstemmed Clozapine-induced Supraventricular Tachycardia and its Treatment with Verapamil
title_short Clozapine-induced Supraventricular Tachycardia and its Treatment with Verapamil
title_sort clozapine-induced supraventricular tachycardia and its treatment with verapamil
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649798/
https://www.ncbi.nlm.nih.gov/pubmed/26664091
http://dx.doi.org/10.4103/0253-7176.162925
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