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Correcting positional correlations in Affymetrix® Genome Chips

We report and model a previously undescribed systematic error causing spurious excess correlations that depend on the distance between probes on Affymetrix® microarrays. The phenomenon affects pairs of features with large chip separations, up to over 100 probes apart. The effect may have a significa...

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Detalles Bibliográficos
Autores principales: Homouz, Dirar, Chen, Gang, Kudlicki, Andrzej S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649851/
https://www.ncbi.nlm.nih.gov/pubmed/25767049
http://dx.doi.org/10.1038/srep09078