Unraveling the molecular architecture of a G protein-coupled receptor/β-arrestin/Erk module complex

β-arrestins serve as signaling scaffolds downstream of G protein-coupled receptors, and thus play a crucial role in a plethora of cellular processes. Although it is largely accepted that the ability of β-arrestins to interact simultaneously with many protein partners is key in G protein-independent...

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Detalles Bibliográficos
Autores principales: Bourquard, Thomas, Landomiel, Flavie, Reiter, Eric, Crépieux, Pascale, Ritchie, David W., Azé, Jérôme, Poupon, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649906/
https://www.ncbi.nlm.nih.gov/pubmed/26030356
http://dx.doi.org/10.1038/srep10760

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