Piperlongumine and immune cytokine TRAIL synergize to promote tumor death

Malignant transformation results in increased levels of reactive oxygen species (ROS). Adaption to this toxic stress allows cancer cells to proliferate. Recently, piperlongumine (PL), a natural alkaloid, was identified to exhibit novel anticancer effects by targeting ROS signaling. PL induces apopto...

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Detalles Bibliográficos
Autores principales: Li, Jiahe, Sharkey, Charles C., King, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649998/
https://www.ncbi.nlm.nih.gov/pubmed/25984950
http://dx.doi.org/10.1038/srep09987

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649998/
https://www.ncbi.nlm.nih.gov/pubmed/25984950
http://dx.doi.org/10.1038/srep09987

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