Cargando…

Concomitant surgical ablation for atrial fibrillation (AF) in patients with significant atrial dilation >55 mm. Worth the effort?

BACKGROUND: Concomitant Surgical AF ablation is an established procedure, recommended in guidelines. However many surgeons are reluctant to perform AF ablation in patients with significantly enlarged left atrium. We therefore analyzed outcomes of patients with left-atrial diameter >55 mm undergoi...

Descripción completa

Detalles Bibliográficos
Autores principales: Pecha, Simon, Hakmi, Samer, Subbotina, Irina, Willems, Stephan, Reichenspurner, Hermann, Wagner, Florian Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650117/
https://www.ncbi.nlm.nih.gov/pubmed/26577821
http://dx.doi.org/10.1186/s13019-015-0337-3
_version_ 1782401450137092096
author Pecha, Simon
Hakmi, Samer
Subbotina, Irina
Willems, Stephan
Reichenspurner, Hermann
Wagner, Florian Mathias
author_facet Pecha, Simon
Hakmi, Samer
Subbotina, Irina
Willems, Stephan
Reichenspurner, Hermann
Wagner, Florian Mathias
author_sort Pecha, Simon
collection PubMed
description BACKGROUND: Concomitant Surgical AF ablation is an established procedure, recommended in guidelines. However many surgeons are reluctant to perform AF ablation in patients with significantly enlarged left atrium. We therefore analyzed outcomes of patients with left-atrial diameter >55 mm undergoing concomitant AF ablation. METHODS: Between 05/2003 and 12/2012 124 patients with significantly enlarged left-atrium >55 mm underwent concomitant surgical AF ablation. Rhythm monitoring was accomplished by implantable loop recorder (ILR) interrogation (n = 54), or 24-h Holter-ECG (n = 70). Successful ablation was defined as AF Burden <0.5 % in ILR interrogation or absence of AF episode >30 s in 24-h Holter-ECG. Primary endpoint of the study was freedom from AF at 12 months follow-up. RESULTS: Mean patient’s age was 65.7+/−9.6 years, 69.4 % were male. No major ablation or ILR related complications occurred. Mean LA diameter was 60.7+/−4.4 mm. Survival rate at one-year follow up was 94.4 %. 11 (8.8 %) patients received additional catheter-based ablation, while 23 (18.5 %) had an electrical cardioversion during follow-up period. Overall freedom from AF rate after one-year follow-up was 64.4 % and 59.4 % off antiarrhythmic drugs respectively. Logistic regression analysis identified preoperative paroxysmal AF, duration of AF and LA diameter > 70 mm as predictors for rhythm outcome at 12 months follow-up. CONCLUSION: In this patient cohort with significantly enlarged LA diameter, concomitant surgical AF ablation provided freedom from AF of 64.4 % after one-year follow-up. However in this patient population, an accurate postoperative care with interventions like medical or- electrical cardioversion and additional catheter based ablation is necessary to achieve satisfactory results.
format Online
Article
Text
id pubmed-4650117
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-46501172015-11-19 Concomitant surgical ablation for atrial fibrillation (AF) in patients with significant atrial dilation >55 mm. Worth the effort? Pecha, Simon Hakmi, Samer Subbotina, Irina Willems, Stephan Reichenspurner, Hermann Wagner, Florian Mathias J Cardiothorac Surg Research Article BACKGROUND: Concomitant Surgical AF ablation is an established procedure, recommended in guidelines. However many surgeons are reluctant to perform AF ablation in patients with significantly enlarged left atrium. We therefore analyzed outcomes of patients with left-atrial diameter >55 mm undergoing concomitant AF ablation. METHODS: Between 05/2003 and 12/2012 124 patients with significantly enlarged left-atrium >55 mm underwent concomitant surgical AF ablation. Rhythm monitoring was accomplished by implantable loop recorder (ILR) interrogation (n = 54), or 24-h Holter-ECG (n = 70). Successful ablation was defined as AF Burden <0.5 % in ILR interrogation or absence of AF episode >30 s in 24-h Holter-ECG. Primary endpoint of the study was freedom from AF at 12 months follow-up. RESULTS: Mean patient’s age was 65.7+/−9.6 years, 69.4 % were male. No major ablation or ILR related complications occurred. Mean LA diameter was 60.7+/−4.4 mm. Survival rate at one-year follow up was 94.4 %. 11 (8.8 %) patients received additional catheter-based ablation, while 23 (18.5 %) had an electrical cardioversion during follow-up period. Overall freedom from AF rate after one-year follow-up was 64.4 % and 59.4 % off antiarrhythmic drugs respectively. Logistic regression analysis identified preoperative paroxysmal AF, duration of AF and LA diameter > 70 mm as predictors for rhythm outcome at 12 months follow-up. CONCLUSION: In this patient cohort with significantly enlarged LA diameter, concomitant surgical AF ablation provided freedom from AF of 64.4 % after one-year follow-up. However in this patient population, an accurate postoperative care with interventions like medical or- electrical cardioversion and additional catheter based ablation is necessary to achieve satisfactory results. BioMed Central 2015-11-14 /pmc/articles/PMC4650117/ /pubmed/26577821 http://dx.doi.org/10.1186/s13019-015-0337-3 Text en © Pecha et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Pecha, Simon
Hakmi, Samer
Subbotina, Irina
Willems, Stephan
Reichenspurner, Hermann
Wagner, Florian Mathias
Concomitant surgical ablation for atrial fibrillation (AF) in patients with significant atrial dilation >55 mm. Worth the effort?
title Concomitant surgical ablation for atrial fibrillation (AF) in patients with significant atrial dilation >55 mm. Worth the effort?
title_full Concomitant surgical ablation for atrial fibrillation (AF) in patients with significant atrial dilation >55 mm. Worth the effort?
title_fullStr Concomitant surgical ablation for atrial fibrillation (AF) in patients with significant atrial dilation >55 mm. Worth the effort?
title_full_unstemmed Concomitant surgical ablation for atrial fibrillation (AF) in patients with significant atrial dilation >55 mm. Worth the effort?
title_short Concomitant surgical ablation for atrial fibrillation (AF) in patients with significant atrial dilation >55 mm. Worth the effort?
title_sort concomitant surgical ablation for atrial fibrillation (af) in patients with significant atrial dilation >55 mm. worth the effort?
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650117/
https://www.ncbi.nlm.nih.gov/pubmed/26577821
http://dx.doi.org/10.1186/s13019-015-0337-3
work_keys_str_mv AT pechasimon concomitantsurgicalablationforatrialfibrillationafinpatientswithsignificantatrialdilation55mmworththeeffort
AT hakmisamer concomitantsurgicalablationforatrialfibrillationafinpatientswithsignificantatrialdilation55mmworththeeffort
AT subbotinairina concomitantsurgicalablationforatrialfibrillationafinpatientswithsignificantatrialdilation55mmworththeeffort
AT willemsstephan concomitantsurgicalablationforatrialfibrillationafinpatientswithsignificantatrialdilation55mmworththeeffort
AT reichenspurnerhermann concomitantsurgicalablationforatrialfibrillationafinpatientswithsignificantatrialdilation55mmworththeeffort
AT wagnerflorianmathias concomitantsurgicalablationforatrialfibrillationafinpatientswithsignificantatrialdilation55mmworththeeffort