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The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength
BACKGROUND: Ergogenic aides are widely used by fitness enthusiasts and athletes to increase performance. Alpha glycerylphosphorylcholine (A-GPC) has demonstrated some initial promise in changing explosive performance. The purpose of the present investigation was to determine if 6 days of supplementa...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650143/ https://www.ncbi.nlm.nih.gov/pubmed/26582972 http://dx.doi.org/10.1186/s12970-015-0103-x |
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author | Bellar, David LeBlanc, Nina R. Campbell, Brian |
author_facet | Bellar, David LeBlanc, Nina R. Campbell, Brian |
author_sort | Bellar, David |
collection | PubMed |
description | BACKGROUND: Ergogenic aides are widely used by fitness enthusiasts and athletes to increase performance. Alpha glycerylphosphorylcholine (A-GPC) has demonstrated some initial promise in changing explosive performance. The purpose of the present investigation was to determine if 6 days of supplementation with A-GPC would augment isometric force production compared to a placebo. METHODS: Thirteen college-aged males (Means ± SD; Age: 21.9 ± 2.2 years, Height: 180.3 ± 7.7 cm, Weight: 87.6 ± 15.6 kg; VO(2) max: 40.08 ± 7.23 ml O(2)*Kg(−1)*min(−1), Body Fat: 17.5 ± 4.6 %) gave written informed consent to participate in the study. The study was a double blind, placebo controlled, cross-over design. The participants reported to the lab for an initial visit where they were familiarized with the isometric mid thigh pull in a custom squat cage on a force platform and upper body isometric test against a high frequency load cell, and baseline measurements were taken for both. The participant then consumed either 600 mg per day of A-GPC or placebo and at the end of 6 days performed isometric mid thigh pulls and an upper body isometric test. A one-week washout period was used before the participants’ baseline was re-measured and crossed over to the other treatment. RESULTS: The A-GPC treatment resulted in significantly greater isometric mid thigh pull peak force change from baseline (t = 1.76, p = 0.044) compared with placebo (A-GPC: 98.8. ± 236.9 N vs Placebo: −39.0 ± 170.9 N). For the upper body test the A-GPC treatment trended towards greater change from baseline force production (A-GPC: 50.9 ± 167.2 N Placebo: −14.9 ± 114.9 N) but failed to obtain statistical significance (t = 1.16, p = 0.127). CONCLUSIONS: A-GPC is effective at increasing lower body force production after 6 days of supplementation. Sport performance coaches can consider adding A-GPC to the diet of speed and power athletes to enhance muscle performance. |
format | Online Article Text |
id | pubmed-4650143 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-46501432015-11-19 The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength Bellar, David LeBlanc, Nina R. Campbell, Brian J Int Soc Sports Nutr Research Article BACKGROUND: Ergogenic aides are widely used by fitness enthusiasts and athletes to increase performance. Alpha glycerylphosphorylcholine (A-GPC) has demonstrated some initial promise in changing explosive performance. The purpose of the present investigation was to determine if 6 days of supplementation with A-GPC would augment isometric force production compared to a placebo. METHODS: Thirteen college-aged males (Means ± SD; Age: 21.9 ± 2.2 years, Height: 180.3 ± 7.7 cm, Weight: 87.6 ± 15.6 kg; VO(2) max: 40.08 ± 7.23 ml O(2)*Kg(−1)*min(−1), Body Fat: 17.5 ± 4.6 %) gave written informed consent to participate in the study. The study was a double blind, placebo controlled, cross-over design. The participants reported to the lab for an initial visit where they were familiarized with the isometric mid thigh pull in a custom squat cage on a force platform and upper body isometric test against a high frequency load cell, and baseline measurements were taken for both. The participant then consumed either 600 mg per day of A-GPC or placebo and at the end of 6 days performed isometric mid thigh pulls and an upper body isometric test. A one-week washout period was used before the participants’ baseline was re-measured and crossed over to the other treatment. RESULTS: The A-GPC treatment resulted in significantly greater isometric mid thigh pull peak force change from baseline (t = 1.76, p = 0.044) compared with placebo (A-GPC: 98.8. ± 236.9 N vs Placebo: −39.0 ± 170.9 N). For the upper body test the A-GPC treatment trended towards greater change from baseline force production (A-GPC: 50.9 ± 167.2 N Placebo: −14.9 ± 114.9 N) but failed to obtain statistical significance (t = 1.16, p = 0.127). CONCLUSIONS: A-GPC is effective at increasing lower body force production after 6 days of supplementation. Sport performance coaches can consider adding A-GPC to the diet of speed and power athletes to enhance muscle performance. BioMed Central 2015-11-17 /pmc/articles/PMC4650143/ /pubmed/26582972 http://dx.doi.org/10.1186/s12970-015-0103-x Text en © Bellar et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Bellar, David LeBlanc, Nina R. Campbell, Brian The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength |
title | The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength |
title_full | The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength |
title_fullStr | The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength |
title_full_unstemmed | The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength |
title_short | The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength |
title_sort | effect of 6 days of alpha glycerylphosphorylcholine on isometric strength |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650143/ https://www.ncbi.nlm.nih.gov/pubmed/26582972 http://dx.doi.org/10.1186/s12970-015-0103-x |
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