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The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength

BACKGROUND: Ergogenic aides are widely used by fitness enthusiasts and athletes to increase performance. Alpha glycerylphosphorylcholine (A-GPC) has demonstrated some initial promise in changing explosive performance. The purpose of the present investigation was to determine if 6 days of supplementa...

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Autores principales: Bellar, David, LeBlanc, Nina R., Campbell, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650143/
https://www.ncbi.nlm.nih.gov/pubmed/26582972
http://dx.doi.org/10.1186/s12970-015-0103-x
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author Bellar, David
LeBlanc, Nina R.
Campbell, Brian
author_facet Bellar, David
LeBlanc, Nina R.
Campbell, Brian
author_sort Bellar, David
collection PubMed
description BACKGROUND: Ergogenic aides are widely used by fitness enthusiasts and athletes to increase performance. Alpha glycerylphosphorylcholine (A-GPC) has demonstrated some initial promise in changing explosive performance. The purpose of the present investigation was to determine if 6 days of supplementation with A-GPC would augment isometric force production compared to a placebo. METHODS: Thirteen college-aged males (Means ± SD; Age: 21.9 ± 2.2 years, Height: 180.3 ± 7.7 cm, Weight: 87.6 ± 15.6 kg; VO(2) max: 40.08 ± 7.23 ml O(2)*Kg(−1)*min(−1), Body Fat: 17.5 ± 4.6 %) gave written informed consent to participate in the study. The study was a double blind, placebo controlled, cross-over design. The participants reported to the lab for an initial visit where they were familiarized with the isometric mid thigh pull in a custom squat cage on a force platform and upper body isometric test against a high frequency load cell, and baseline measurements were taken for both. The participant then consumed either 600 mg per day of A-GPC or placebo and at the end of 6 days performed isometric mid thigh pulls and an upper body isometric test. A one-week washout period was used before the participants’ baseline was re-measured and crossed over to the other treatment. RESULTS: The A-GPC treatment resulted in significantly greater isometric mid thigh pull peak force change from baseline (t = 1.76, p = 0.044) compared with placebo (A-GPC: 98.8. ± 236.9 N vs Placebo: −39.0 ± 170.9 N). For the upper body test the A-GPC treatment trended towards greater change from baseline force production (A-GPC: 50.9 ± 167.2 N Placebo: −14.9 ± 114.9 N) but failed to obtain statistical significance (t = 1.16, p = 0.127). CONCLUSIONS: A-GPC is effective at increasing lower body force production after 6 days of supplementation. Sport performance coaches can consider adding A-GPC to the diet of speed and power athletes to enhance muscle performance.
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spelling pubmed-46501432015-11-19 The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength Bellar, David LeBlanc, Nina R. Campbell, Brian J Int Soc Sports Nutr Research Article BACKGROUND: Ergogenic aides are widely used by fitness enthusiasts and athletes to increase performance. Alpha glycerylphosphorylcholine (A-GPC) has demonstrated some initial promise in changing explosive performance. The purpose of the present investigation was to determine if 6 days of supplementation with A-GPC would augment isometric force production compared to a placebo. METHODS: Thirteen college-aged males (Means ± SD; Age: 21.9 ± 2.2 years, Height: 180.3 ± 7.7 cm, Weight: 87.6 ± 15.6 kg; VO(2) max: 40.08 ± 7.23 ml O(2)*Kg(−1)*min(−1), Body Fat: 17.5 ± 4.6 %) gave written informed consent to participate in the study. The study was a double blind, placebo controlled, cross-over design. The participants reported to the lab for an initial visit where they were familiarized with the isometric mid thigh pull in a custom squat cage on a force platform and upper body isometric test against a high frequency load cell, and baseline measurements were taken for both. The participant then consumed either 600 mg per day of A-GPC or placebo and at the end of 6 days performed isometric mid thigh pulls and an upper body isometric test. A one-week washout period was used before the participants’ baseline was re-measured and crossed over to the other treatment. RESULTS: The A-GPC treatment resulted in significantly greater isometric mid thigh pull peak force change from baseline (t = 1.76, p = 0.044) compared with placebo (A-GPC: 98.8. ± 236.9 N vs Placebo: −39.0 ± 170.9 N). For the upper body test the A-GPC treatment trended towards greater change from baseline force production (A-GPC: 50.9 ± 167.2 N Placebo: −14.9 ± 114.9 N) but failed to obtain statistical significance (t = 1.16, p = 0.127). CONCLUSIONS: A-GPC is effective at increasing lower body force production after 6 days of supplementation. Sport performance coaches can consider adding A-GPC to the diet of speed and power athletes to enhance muscle performance. BioMed Central 2015-11-17 /pmc/articles/PMC4650143/ /pubmed/26582972 http://dx.doi.org/10.1186/s12970-015-0103-x Text en © Bellar et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Bellar, David
LeBlanc, Nina R.
Campbell, Brian
The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength
title The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength
title_full The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength
title_fullStr The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength
title_full_unstemmed The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength
title_short The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength
title_sort effect of 6 days of alpha glycerylphosphorylcholine on isometric strength
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650143/
https://www.ncbi.nlm.nih.gov/pubmed/26582972
http://dx.doi.org/10.1186/s12970-015-0103-x
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