Smac mimetic-induced upregulation of interferon-β sensitizes glioblastoma to temozolomide-induced cell death

Inhibitor of apoptosis (IAP) proteins are frequently expressed at high levels in cancer cells and represent attractive therapeutic targets. We previously reported that the Smac (second mitochondria-derived activator of caspases) mimetic BV6, which antagonizes IAP proteins, sensitizes glioblastoma ce...

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Detalles Bibliográficos
Autores principales: Marschall, V, Fulda, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650438/
https://www.ncbi.nlm.nih.gov/pubmed/26379193
http://dx.doi.org/10.1038/cddis.2015.235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650438/
https://www.ncbi.nlm.nih.gov/pubmed/26379193
http://dx.doi.org/10.1038/cddis.2015.235

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