ER stress induces NLRP3 inflammasome activation and hepatocyte death

The incidence of chronic liver disease is constantly increasing, owing to the obesity epidemic. However, the causes and mechanisms of inflammation-mediated liver damage remain poorly understood. Endoplasmic reticulum (ER) stress is an initiator of cell death and inflammatory mechanisms. Although obe...

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Detalles Bibliográficos
Autores principales: Lebeaupin, C, Proics, E, de Bieville, C H D, Rousseau, D, Bonnafous, S, Patouraux, S, Adam, G, Lavallard, V J, Rovere, C, Le Thuc, O, Saint-Paul, M C, Anty, R, Schneck, A S, Iannelli, A, Gugenheim, J, Tran, A, Gual, P, Bailly-Maitre, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650444/
https://www.ncbi.nlm.nih.gov/pubmed/26355342
http://dx.doi.org/10.1038/cddis.2015.248

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