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FOXM1 and polo-like kinase 1 are co-ordinately overexpressed in patients with gastric adenocarcinomas

BACKGROUND: Gastric cancers present late in life with advanced disease and carry a poor prognosis. Polo-like Kinase 1 (PLK1) is a mitotic kinase with regulatory functions during G2/M and mitosis in the cell cycle. In mammalian cells, there is an intricate co-regulatory relationship between PLK1 and...

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Detalles Bibliográficos
Autores principales: Dibb, M., Han, N., Choudhury, J., Hayes, S., Valentine, H., West, C., Sharrocks, AD, Ang, Yeng S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650505/
https://www.ncbi.nlm.nih.gov/pubmed/26576650
http://dx.doi.org/10.1186/s13104-015-1658-y