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NF-κB inhibition reveals a novel role for HGF during skeletal muscle repair

The transcription factor nuclear factor κB (NF-κB)/p65 is the master regulator of inflammation in Duchenne muscular dystrophy (DMD). Disease severity is reduced by NF-κB inhibition in the mdx mouse, a murine DMD model; however, therapeutic targeting of NF-κB remains problematic for patients because...

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Detalles Bibliográficos
Autores principales: Proto, J D, Tang, Y, Lu, A, Chen, W C W, Stahl, E, Poddar, M, Beckman, S A, Robbins, P D, Nidernhofer, L J, Imbrogno, K, Hannigan, T, Mars, W M, Wang, B, Huard, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650539/
https://www.ncbi.nlm.nih.gov/pubmed/25906153
http://dx.doi.org/10.1038/cddis.2015.66

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