Macrophage- and RIP3-dependent inflammasome activation exacerbates retinal detachment-induced photoreceptor cell death

Detachment of photoreceptors from the retinal pigment epithelium is seen in various retinal disorders, resulting in photoreceptor death and subsequent vision loss. Cell death results in the release of endogenous molecules that activate molecular platforms containing caspase-1, termed inflammasomes....

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Detalles Bibliográficos
Autores principales: Kataoka, K, Matsumoto, H, Kaneko, H, Notomi, S, Takeuchi, K, Sweigard, J H, Atik, A, Murakami, Y, Connor, K M, Terasaki, H, Miller, J W, Vavvas, D G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650542/
https://www.ncbi.nlm.nih.gov/pubmed/25906154
http://dx.doi.org/10.1038/cddis.2015.73

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