Cargando…
Decay in survival motor neuron and plastin 3 levels during differentiation of iPSC-derived human motor neurons
Spinal muscular atrophy (SMA) is a neuromuscular disease caused by mutations in Survival Motor Neuron 1 (SMN1), leading to degeneration of alpha motor neurons (MNs) but also affecting other cell types. Induced pluripotent stem cell (iPSC)-derived human MN models from severe SMA patients have shown r...
Autores principales: | Boza-Morán, María G, Martínez-Hernández, Rebeca, Bernal, Sara, Wanisch, Klaus, Also-Rallo, Eva, Le Heron, Anita, Alías, Laura, Denis, Cécile, Girard, Mathilde, Yee, Jiing-Kuan, Tizzano, Eduardo F., Yáñez-Muñoz, Rafael J |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650562/ https://www.ncbi.nlm.nih.gov/pubmed/26114395 http://dx.doi.org/10.1038/srep11696 |
Ejemplares similares
-
An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids
por: Castellanos-Montiel, María José, et al.
Publicado: (2023) -
Microglia Influence Neurofilament Deposition in ALS iPSC-Derived Motor Neurons
por: Allison, Reilly L., et al.
Publicado: (2022) -
iPSC motor neurons, but not other derived cell types, capture gene expression changes in postmortem sporadic ALS motor neurons
por: Held, Aaron, et al.
Publicado: (2023) -
Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects
por: Workman, Michael J., et al.
Publicado: (2023) -
Global transcriptome profile of the developmental principles of in vitro iPSC-to-motor neuron differentiation
por: Solomon, Emilia, et al.
Publicado: (2021)