Cationic nanocarriers induce cell necrosis through impairment of Na(+)/K(+)-ATPase and cause subsequent inflammatory response

Nanocarriers with positive surface charges are known for their toxicity which has limited their clinical applications. The mechanism underlying their toxicity, such as the induction of inflammatory response, remains largely unknown. In the present study we found that injection of cationic nanocarrie...

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Detalles Bibliográficos
Autores principales: Wei, Xiawei, Shao, Bin, He, Zhiyao, Ye, Tinghong, Luo, Min, Sang, Yaxiong, Liang, Xiao, Wang, Wei, Luo, Shuntao, Yang, Shengyong, Zhang, Shuang, Gong, Changyang, Gou, Maling, Deng, Hongxing, Zhao, Yinglan, Yang, Hanshuo, Deng, Senyi, Zhao, Chengjian, Yang, Li, Qian, Zhiyong, Li, Jiong, Sun, Xun, Han, Jiahuai, Jiang, Chengyu, Wu, Min, Zhang, Zhirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650577/
https://www.ncbi.nlm.nih.gov/pubmed/25613571
http://dx.doi.org/10.1038/cr.2015.9

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