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Pancreatic alpha-cells from female mice undergo morphofunctional changes during compensatory adaptations of the endocrine pancreas to diet-induced obesity
Obesity is frequently associated with insulin resistance. To compensate for this situation and maintain normoglycaemia, pancreatic beta-cells undergo several morphofunctional adaptations, which result in insulin hypersecretion and hyperinsulinaemia. However, no information exists about pancreatic al...
Autores principales: | Merino, Beatriz, Alonso-Magdalena, Paloma, Lluesma, Mónica, Ñeco, Patricia, Gonzalez, Alejandro, Marroquí, Laura, García-Arévalo, Marta, Nadal, Angel, Quesada, Ivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650619/ https://www.ncbi.nlm.nih.gov/pubmed/26108563 http://dx.doi.org/10.1038/srep11622 |
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