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Identification of a distinct population of CD133(+)CXCR4(+) cancer stem cells in ovarian cancer
CD133 and CXCR4 were evaluated in the NCI-60 cell lines to identify cancer stem cell rich populations. Screening revealed that, ovarian OVCAR-3, -4 and -5 and colon cancer HT-29, HCT-116 and SW620 over expressed both proteins. We aimed to isolate cells with stem cell features sorting the cells expre...
Autores principales: | Cioffi, Michele, D’Alterio, Crescenzo, Camerlingo, Rosalba, Tirino, Virginia, Consales, Claudia, Riccio, Anna, Ieranò, Caterina, Cecere, Sabrina Chiara, Losito, Nunzia Simona, Greggi, Stefano, Pignata, Sandro, Pirozzi, Giuseppe, Scala, Stefania |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650662/ https://www.ncbi.nlm.nih.gov/pubmed/26020117 http://dx.doi.org/10.1038/srep10357 |
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