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SUMO1 Affects Synaptic Function, Spine Density and Memory

Small ubiquitin-like modifier-1 (SUMO1) plays a number of roles in cellular events and recent evidence has given momentum for its contributions to neuronal development and function. Here, we have generated a SUMO1 transgenic mouse model with exclusive overexpression in neurons in an effort to identi...

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Detalles Bibliográficos
Autores principales: Matsuzaki, Shinsuke, Lee, Linda, Knock, Erin, Srikumar, Tharan, Sakurai, Mikako, Hazrati, Lili-Naz, Katayama, Taiichi, Staniszewski, Agnieszka, Raught, Brian, Arancio, Ottavio, Fraser, Paul E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650663/
https://www.ncbi.nlm.nih.gov/pubmed/26022678
http://dx.doi.org/10.1038/srep10730