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High-throughput sequencing enhanced phage display enables the identification of patient-specific epitope motifs in serum
Phage display is a prominent screening technique with a multitude of applications including therapeutic antibody development and mapping of antigen epitopes. In this study, phages were selected based on their interaction with patient serum and exhaustively characterised by high-throughput sequencing...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650709/ https://www.ncbi.nlm.nih.gov/pubmed/26246327 http://dx.doi.org/10.1038/srep12913 |