Cargando…

Metabolic stress induces a Wnt-dependent cancer stem cell-like state transition

Reciprocal interactions between cancer cells and the tumor microenvironment drive multiple clinically significant behaviors including dormancy, invasion, and metastasis as well as therapy resistance. These microenvironment-dependent phenotypes share typical characteristics with cancer stem cells (CS...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, E, Yang, J, Ku, M, Kim, N H, Park, Y, Park, C B, Suh, J-S, Park, E S, Yook, J I, Mills, G B, Huh, Y-M, Cheong, J-H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650724/ https://www.ncbi.nlm.nih.gov/pubmed/26136078 http://dx.doi.org/10.1038/cddis.2015.171

Ejemplares similares

Integrated omics-analysis reveals Wnt-mediated NAD(+) metabolic reprogramming in cancer stem-like cells
por: Lee, Jueun, et al.
Publicado: (2016)

Interferon consensus sequence-binding protein (ICSBP) promotes epithelial-to-mesenchymal transition (EMT)-like phenomena, cell-motility, and invasion via TGF-β signaling in U2OS cells
por: Sung, J Y, et al.
Publicado: (2014)

Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling
por: Jung, H, et al.
Publicado: (2013)

MiR-29b controls fetal mouse neurogenesis by regulating ICAT-mediated Wnt/β-catenin signaling
por: Shin, J, et al.
Publicado: (2014)

Efficacy of screening for gastric cancer in a Korean adult population: a case-control study.
por: Kim, Y. S., et al.
Publicado: (2000)

The antidepressant roles of Wnt2 and Wnt3 in stress-induced depression-like behaviors
por: Zhou, W-J, et al.
Publicado: (2016)

Autophagy-dependent generation of Axin2+ cancer stem-like cells promotes hepatocarcinogenesis in liver cirrhosis
por: Li, J, et al.
Publicado: (2017)

Bimodal function of chromatin remodeler Hmga1 in neural crest induction and Wnt-dependent emigration
por: Gandhi, Shashank, et al.
Publicado: (2020)

Aspirin Rescues Wnt-Driven Stem-like Phenotype in Human Intestinal Organoids and Increases the Wnt Antagonist Dickkopf-1
por: Dunbar, Karen, et al.
Publicado: (2020)

WNT inhibition creates a BRCA‐like state in Wnt‐addicted cancer
por: Kaur, Amanpreet, et al.
Publicado: (2021)

iNKT cells prevent obesity-induced hepatic steatosis in mice in a C-C chemokine receptor 7-dependent manner
por: Kim, H M, et al.
Publicado: (2018)

Wnt Pathway Activity in Breast Cancer Sub-Types and Stem-Like Cells
por: Lamb, Rebecca, et al.
Publicado: (2013)

Clinical impacts of tumor cell contamination of hematopoietic stem cell products in metastatic breast cancer patients undergoing autologous peripheral blood stem cell transplantation: multicenter trial.
por: Ahn, M. J., et al.
Publicado: (2001)

2,4,5-Trimethoxyldalbergiquinol promotes osteoblastic differentiation and mineralization via the BMP and Wnt/β-catenin pathway
por: Yun, H-M, et al.
Publicado: (2015)

Establishment and characterisation of six human biliary tract cancer cell lines
por: Ku, J-L, et al.
Publicado: (2002)

Adjuvant chemotherapy for gastric cancer: a randomised phase 3 trial of mitomycin-C plus either short-term doxifluridine or long-term doxifluridine plus cisplatin after curative D2 gastrectomy (AMC0201)
por: Kang, Y-K, et al.
Publicado: (2013)

The effects of mesenchymal stem cells injected via different routes on modified IL-12-mediated antitumor activity
por: Seo, S H, et al.
Publicado: (2011)

Priming with Toll-like receptor 3 agonist or interferon-gamma enhances the therapeutic effects of human mesenchymal stem cells in a murine model of atopic dermatitis
por: Park, Arum, et al.
Publicado: (2019)

Single-cell trajectory analysis reveals a CD9 positive state to contribute to exit from stem cell-like and embryonic diapause states and transit to drug-resistant states
por: Li, Xi, et al.
Publicado: (2023)

API5 confers cancer stem cell-like properties through the FGF2-NANOG axis
por: Song, K-H, et al.
Publicado: (2017)

Therapeutic embolization of the dural arteriovenous malformation involving the jugular bulb.
por: Park, J. Y., et al.
Publicado: (2001)

MacroH2A1 downregulation enhances the stem-like properties of bladder cancer cells by transactivation of Lin28B
por: Park, S-J, et al.
Publicado: (2016)

The stem-like Stat3-responsive cells of zebrafish intestine are Wnt/β-catenin dependent
por: Peron, Margherita, et al.
Publicado: (2020)

Wnt ligand presentation and reception: from the stem cell niche to tissue engineering
por: Mills, Kate M., et al.
Publicado: (2017)

Dishevelling Wnt and Hippo
por: Kim, Nam Hee, et al.
Publicado: (2018)

Transcriptional repression of cancer stem cell marker CD133 by tumor suppressor p53
por: Park, E K, et al.
Publicado: (2015)

Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells
por: Huels, D. J., et al.
Publicado: (2018)

The role of thioredoxin 1 in the mycophenolic acid-induced apoptosis of insulin-producing cells
por: Huh, K H, et al.
Publicado: (2013)

WNT5A Interacts With FZD5 and LRP5 to Regulate Proliferation and Self-Renewal of Endometrial Mesenchymal Stem-Like Cells
por: Li, Tianqi, et al.
Publicado: (2022)

P01.20. The effect of WIN-34B on cartilage protection and regeneration by chondrogenesis from subchondral bone in vitro and in vivo
por: Huh, J, et al.
Publicado: (2012)

WNT Ligand Dependencies in Pancreatic Cancer
por: Aguilera, Kristina Y., et al.
Publicado: (2021)

Threshold dependence of strip clusters for the forward region resistive plate chamber of the CMS/LHC experiment
por: Ahn, S H, et al.
Publicado: (2003)

Deformation mechanisms to ameliorate the mechanical properties of novel TRIP/TWIP Co-Cr-Mo-(Cu) ultrafine eutectic alloys
por: Kim, J. T., et al.
Publicado: (2017)

YAP-dependent Wnt5a induction in hypertrophic adipocytes restrains adiposity
por: Lee, Gwan-Jun, et al.
Publicado: (2022)

DNA-mediated immunization of mice with plasmid encoding HBs antigen.
por: Yoon, S. J., et al.
Publicado: (1999)

Performance of the BACCUS Transition Radiation Detector
por: Picot-Clémente, Nicolas, et al.
Publicado: (2017)

The levels of MDM2 protein are decreased by a proteasome-mediated proteolysis prior to caspase-3-dependent pRb and PARP cleavages.
por: Cho, J. W., et al.
Publicado: (2001)

Thyroglobulin synthesis of oxyphilic cells in various types of neoplastic and autoimmune thyroid diseases.
por: Hwang, T. S., et al.
Publicado: (1990)

The small molecule indirubin-3′-oxime activates Wnt/β-catenin signaling and inhibits adipocyte differentiation and obesity
por: Choi, O M, et al.
Publicado: (2014)

A hypoxia-dependent upregulation of hypoxia-inducible factor-1 by nuclear factor-κB promotes gastric tumour growth and angiogenesis
por: Nam, S Y, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_07b44ovapb2eeevtd1oi4kbsor