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Generic amyloidogenicity of mammalian prion proteins from species susceptible and resistant to prions
Prion diseases are lethal, infectious diseases associated with prion protein (PrP) misfolding. A large number of mammals are susceptible to both sporadic and acquired prion diseases. Although PrP is highly conserved and ubiquitously expressed in all mammals, not all species exhibit prion disease. By...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650755/ https://www.ncbi.nlm.nih.gov/pubmed/25960067 http://dx.doi.org/10.1038/srep10101 |